|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Rat, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human CXG2|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: connexin 47 type A; connexin 47 type C; connexin 47 type D; Connexin-46.6; Connexin-47; Cx46.6; Cx47; CXG2; Gap junction alpha-12 protein; Gap junction gamma-2 protein; gap junction membrane channel protein alpha 12; gap junction protein, alpha 12; gap junction protein, chi 2; gap junction protein, gamma 2, 47kDa; GJA12; GJC2
Gene Aliases: B230382L12Rik; CX46.6; Cx47; GJA12; GJC2; HLD2; LMPH1C; PMLDAR; SPG44
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