|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||1-2 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:100|
|Western Blot (WB)||Assay Dependent|
|Immunofluorescence (IF)||See 2 publications below|
|Western Blot (WB)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Rabbit , Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from an internal region of the mouse, rat, Chinese hamster and golden hamster connexin 57 (Cx57) proteins|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
40-5000 was used in immunofluorescence analysis of Connexin57 (Cx57) on sections of adult mouse retina.
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: connexin 62; Connexin-57; Connexin-62; Cx57; Cx62; Gap junction alpha-10 protein; gap junction membrane channel protein alpha 10; gap junction protein, alpha 10, 62kDa
Gene Aliases: Cx-57; cx57; Cx59; CX62; GJA10
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