|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 270 of Human Coronin 2A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30206 targets Coronin 2A in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30206 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 270 of Human Coronin 2A.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2A; actin-binding protein; CLIPINB; coronin; coronin 2A; coronin, actin binding protein, 2A; coronin, actin-binding protein, 2A; Coronin-2A; coronin-like protein B; IR10; WD protein IR10; WD repeat-containing protein 2; WD-repeat protein 2; WDR2
Gene Aliases: CLIPINB; CORO2A; IR10; WDR2
UniProt ID: (Human) Q92828
Entrez Gene ID: (Human) 7464
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