|Western Blot (WB)||2 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to an N-terminal portion of the murine cripto protein sequence (between residues 1-50).|
|Purification||Antigen affinity chromatography|
|Storage buffer||sodium borate|
|Storage conditions||4° C, store in dark|
In Western blot a band is seen at ~18 kDa representing the core form of Cripto1, and at ~36 kDa reporesenting the glycosylated/ post-translationally modified form.
Suggested positive control: MDA-MB231 (human breast cancer) lysates.
The cripto gene is expressed both in ES cells and during the early phases of embryo development, while, in the adult, it is reactivated in a wide range of epithelial cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CRGF; CRIPTO; cripto growth factor; Cripto-1 growth factor; epidermal growth factor-like Cripto protein; Epidermal growth factor-like cripto protein CR1; teratocarcinoma-derived growth factor; Teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)
Gene Aliases: CR; CR1; CRGF; CRIPTO; TDGF1
UniProt ID: (Human) P13385
Molecular Function: calcium-binding protein
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