|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 172 of Human CtBP2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30001 targets CtBP2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30001 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 172 of Human CtBP2.
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.
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Protein Aliases: C-terminal-binding protein 2; CtBP2; ribeye
Gene Aliases: CTBP2
UniProt ID: (Human) P56545
Entrez Gene ID: (Human) 1488
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