|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 547 and 762 of Human Ctip1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30636 targets Ctip1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30636 immunogen is recombinant protein fragment corresponding to a region within amino acids 547 and 762 of Human Ctip1.
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
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Protein Aliases: B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A-L; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF-interacting protein 1; CTIP1; ecotropic viral integration site; ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein homolog; EVI-9; EVI9; HBFQTL5; Zinc finger protein 856; ZNF856
Gene Aliases: BCL11A; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; CTIP1; EVI9; HBFQTL5; KIAA1809; ZNF856
UniProt ID: (Human) Q9H165
Entrez Gene ID: (Human) 53335
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