|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 592 and 887 of Human Cullin 4B|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29856 targets Cullin 4B in WB applications and shows reactivity with Human samples.
The PA5-29856 immunogen is recombinant protein fragment corresponding to a region within amino acids 592 and 887 of Human Cullin 4B.
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CUL-4B; Cullin-4B; MRXHF2; MRXS15; MRXSC; SFM2
Gene Aliases: CUL-4B; CUL4B; KIAA0695; MRXHF2; MRXS15; MRXSC; SFM2
UniProt ID: (Human) Q13620
Entrez Gene ID: (Human) 8450
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