|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:200|
|Western Blot (WB)||See 80 publications below|
|Immunohistochemistry (IHC)||See 43 publications below|
|Immunoprecipitation (IP)||See 4 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Avian , Rat , Bovine , Human , Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant, full length human protein.|
|Contains||15mM sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-24750 detects Cyclin D1 from human, mouse, rat, and monkey samples. This antibody does not cross-react with other D-type cyclins.
MA1-24750 has been successfully used in Immunocytochemistry, immunohistochemistry (paraffin), immunoprecipitation, and Western blot procedures.
The MA1-24750 immunogen is recombinant, full length human protein.
Cyclin D1 (Bcl-1 oncogene product), is a member of the Cyclin family that help control transition between phases of the cell cycle by acting as regulatory subunits of the Cdks. The D-type Cyclins are composed of three subtypes, Cyclin D1, D2 and D3. Cyclin D1 is essential for control of the cell cycle at the G1/S transitions and interacts with Cdk4 or Cdk6 protein kinases. On the recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Also Cyclin D1 involves in development and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; G1/S-specific cyclin-D1; PRAD-1; PRAD1 oncogene
Gene Aliases: AI327039; bcl-1; BCL1; CCND1; cD1; CycD1; Cyl-1; D11S287E; PRAD1; U21B31
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