|Immunohistochemistry (Paraffin) (IHC (P))||1:25-50|
|Western Blot (WB)||1:100|
|Immunohistochemistry (Frozen) (IHC (F))||See 3 publications below|
|Immunohistochemistry (IHC)||See 216 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 13 publications below|
|Western Blot (WB)||See 25 publications below|
|Miscellaneous PubMed (MISC)||See 2 publications below|
|Immunocytochemistry (ICC)||See 4 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Baboon , Rat , Mouse , Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide from C-terminus of human cyclin D1|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage conditions||4° C|
MA5-14512 targets Cyclin D1/Bcl-1 in IHC (P), ICC/IF and WB applications and shows reactivity with Human and Mouse samples.
The MA5-14512 immunogen is a synthetic peptide from C-terminus of human cyclin D1.
Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; G1/S-specific cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene
Gene Aliases: AI327039; bcl-1; BCL1; CCND1; cD1; CycD1; Cyl-1; D11S287E; PRAD1; U21B31
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