|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
|Western Blot (WB)||See 13 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 5 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Human Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human cyclin E protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14333 targets Cyclin E in FACS, IF, IHC (P), and WB applications and shows reactivity with Human and Mouse samples.
The MA5-14333 immunogen is recombinant human cyclin E protein.
Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues. Qualitative and quantitative alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cyclin Es; cyclin Et; G1/S-specific cyclin-E1
Gene Aliases: AW538188; CCNE; CCNE1; CycE1; pCCNE1
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