|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||1:250|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant protein containing the N-terminal region of human cyclophilin A|
|Storage buffer||tissue culture supernatant|
|Contains||0.1% sodium azide|
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cyclophilin A; Cyclosporin A-binding protein; CYPA; epididymis secretory sperm binding protein Li 69p; N-terminally processed; Peptidyl-prolyl cis-trans isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase A; Rotamase A; SP18; T cell cyclophilin
Gene Aliases: 2700098C05; Cphn; CyP-18; CYPA; CYPH; HEL-S-69p; PPIA
Molecular Function: isomerase
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