|Functional Assay (FN)||2-20 µl|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified human CYP2C19 expressed in E.Coli.|
|Storage buffer||whole serum|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is a specific and potent inhibitor of CYP2C19 activity.
P450 enzymes are divided into two groups: steroidogenic and Xenobiotic. The latter group is comprised of three families 1 ,2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3a, CYP2D6, CYP2C9/10, CYP2C19, CYP2E1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC17; CYPIIC19; cytochrome P-450 II C; cytochrome P450 2C19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450-11A; cytochrome P450-254C; flavoprotein-linked monooxygenase; mephenytoin 4'-hydroxylase; mephenytoin 4-hydroxylase; microsomal monooxygenase; S-mephenytoin 4-hydroxylase; xenobiotic monooxygenase
Gene Aliases: CPCJ; CYP2C; P450C2C; P450IIC19; RP11-400G3.4
UniProt ID: (Human) P33261
Entrez Gene ID: (Human) 1557
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