|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Cytoskeleton preparation extracted from human epidermis by detergent/high salt extraction|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BCIE; BIE; CK-10; CK10; cytokeratin 10; Cytokeratin-10; EHK; K10; keratin; keratin 10, type I; Keratin, type I cytoskeletal 10; Keratin-10; KPP; type I cytoskeletal 10
Gene Aliases: BCIE; BIE; CK10; EHK; K10; KPP; KRT10
UniProt ID: (Human) P13645
Entrez Gene ID: (Human) 3858
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