|Immunohistochemistry (Frozen) (IHC (F))||1:100-1:1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 112 and 472 of Human Cytokeratin 14|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol, 1% BSA|
|Contains||0.025% Proclin 300|
PA5-28002 targets Cytokeratin 14 in IF, IHC (P), and WB applications and shows reactivity with Human, rat, and mouse samples.
The PA5-28002 immunogen is recombinant fragment corresponding to a region within amino acids 112 and 472 of Human Cytokeratin 14.
This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CK-14; CK14; cytokeratin 14; Cytokeratin-14; Dowling-Meara; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; keratin; keratin 14 (epidermolysis bullosa simplex; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; Keratin, type I cytoskeletal 14; Keratin-14; Koebner); NFJ; type I cytoskeletal 14; Type I keratin Ka14
Gene Aliases: AI626930; CK14; EBS3; EBS4; K14; Ka14; Krt-1.14; Krt1-14; KRT14; NFJ
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