|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 331 and 424 of Human Cytokeratin 20|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27250 targets Cytokeratin 20 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27250 immunogen is synthetic peptide corresponding to a region within amino acids 331 and 424 of Human Cytokeratin 20.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CK-20; CK20; cytokeratin 20; Cytokeratin-20; K20; keratin; keratin 20, type I; Keratin, type I cytoskeletal 20; Keratin-20; KRT21; Protein IT; type I cytoskeletal 20
Gene Aliases: CD20; CK-20; CK20; K20; KRT20; KRT21
UniProt ID: (Human) P35900
Entrez Gene ID: (Human) 54474
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