|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunohistochemistry (PFA fixed) (IHC (PFA))||Assay Dependent|
|Western Blot (WB)||1:1000|
|Immunohistochemistry (IHC)||See 6 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse / Ig|
|Immunogen||Human hair keratins from P3X63Ag. 8.653 cells|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
MA1-5765 detects Cytokeratin, AE13 in human and mouse samples.
MA1-5765 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunohistochemistry procedures.
The MA1-5765 immunogen is human hair keratins.
This antibody reacts with acidic 44-46 kDa hair cortex keratins.
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CK-40; Cytokeratin-40; K40; keratin 40, type I; Keratin, type I cytoskeletal 40; Keratin-40; ortholog of type I hair keratin KA36; Type I hair keratin Ka36
Gene Aliases: CK-40; K40; KA36; KRT40
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