|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse|
|Immunogen||Human epidermal keratins from P3 x 63 Ag8 cells|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-5766 detects Cytokeratin K10-1, AE20 in human samples.
MA1-5766 has been successfully used in Western blot and immunohistochemistry procedures.
The MA1-5766 immunogen is human epidermal keratins.
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CK-10; cytokeratin 10; Cytokeratin-10; K10; keratin 10, type I; Keratin, type I cytoskeletal 10; Keratin-10
Gene Aliases: BCIE; BIE; CK10; EHK; K10; KPP; KRT10
UniProt ID: (Human) Q8N175
Entrez Gene ID: (Human) 3858
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