|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 118 and 337 of Human DAP kinase 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29943 targets DAP kinase 2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29943 immunogen is recombinant fragment corresponding to a region within amino acids 118 and 337 of Human DAP kinase 2.
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAP kinase 2; DAP-kinase-related protein 1; DAP-kinase-related protein 1 beta isoform; Death-associated protein kinase 2; DRP-1; DRP1
Gene Aliases: DAPK2; DRP-1; DRP1
UniProt ID: (Human) Q9UIK4
Entrez Gene ID: (Human) 23604
Molecular Function: non-receptor serine/threonine protein kinase
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