|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 52 and 277 of Human DAP3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29850 targets DAP3 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29850 immunogen is recombinant fragment corresponding to a region within amino acids 52 and 277 of Human DAP3.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 28S ribosomal protein S29; 28S ribosomal protein S29, mitochondrial; bMRP-10; DAP-3; Death-associated protein 3; Ionizing radiation resistance conferring protein; mitochondrial; mitochondrial 28S ribosomal protein S29; Mitochondrial small ribosomal subunit protein mS29; MRP-S29; MRPS29; S29mt
Gene Aliases: bMRP-10; DAP-3; DAP3; MRP-S29; MRPS29
UniProt ID: (Human) Q96Q20
Entrez Gene ID: (Human) 7818
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