|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 39 and 300 of Human DDX46|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30336 targets DDX46 in WB applications and shows reactivity with Human samples.
The PA5-30336 immunogen is recombinant protein fragment corresponding to a region within amino acids 39 and 300 of Human DDX46.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; DEAD box protein 46; Probable ATP-dependent RNA helicase DDX46; Prp5; PRP5 homolog; Prp5-like DEAD-box protein; PRPF5; RNA helicase
Gene Aliases: DDX46; KIAA0801; Prp5; PRPF5
UniProt ID: (Human) Q7L014
Entrez Gene ID: (Human) 9879
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