|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment contains a sequence corresponding to a region within amino acids 612 and 811 of DEPDC1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34864 targets DEPDC1 in WB applications and shows reactivity with Human samples.
The PA5-34864 immunogen is recombinant fragment contains a sequence corresponding to a region within amino acids 612 and 811 of DEPDC1.
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5830484J08Rik; cell cycle control protein SDP35; DEP domain-containing protein 1A; DEP.8; DEPDC1-V2; DEPDC1A; SDP35
Gene Aliases: DEP.8; DEPDC1; DEPDC1-V2; DEPDC1A; SDP35
UniProt ID: (Human) Q5TB30
Entrez Gene ID: (Human) 55635
Molecular Function: nucleic acid binding
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