|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 624 and 889 of Human DHX16|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30272 targets DHX16 in WB applications and shows reactivity with Human samples.
The PA5-30272 immunogen is recombinant fragment corresponding to a region within amino acids 624 and 889 of Human DHX16.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent RNA helicase #3; DBP2; DDX16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH-box protein 16; PRO2014; Prp2; PRP8; PRPF2; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase
Gene Aliases: DBP2; DDX16; DHX16; KIAA0577; PRO2014; Prp2; PRP8; PRPF2
UniProt ID: (Human) O60231
Entrez Gene ID: (Human) 8449
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