|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (QTKTSKAKKDQ) corresponding to the internal amino acids of DIAPH1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with human based on sequence homology.
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DFNA1; DIA1; DIAPH1; diaphanous 1; diaphanous homolog 1 (Drosophila); diaphanous-1; diaphanous-related formin 1; Diaphanous-related formin-1; DRF1; FLJ25265; hDIA1; LFHL1; mDIA1; p140mDIA; Protein diaphanous homolog 1
Gene Aliases: D18Wsu154e; Dia1; Diap1; Diaph1; Drf1; p140mDia
UniProt ID: (Mouse) O08808
Entrez Gene ID: (Mouse) 13367
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