|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ATYSSKARLHVCQKI) corresponding to the C-terminus amino acids of DKK2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dickkopf (Xenopus laevis) homolog 2; dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf related protein-2; Dickkopf-2; Dickkopf-related protein 2; DKK-2; DKK2; hDkk-2
Gene Aliases: DKK-2; DKK2; UNQ682/PRO1316
UniProt ID: (Human) Q9UBU2
Entrez Gene ID: (Human) 27123
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