|Immunohistochemistry (Paraffin) (IHC (P))||1-10ug/ml|
|Western Blot (WB)||0.03-0.1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (AAAALLGGEEI) corresponding to the C-terminus amino acids of DKK3|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dickkopf (Xenopus laevis) homolog 3; dickkopf 3; dickkopf 3 homolog; Dickkopf gene 3; dickkopf homolog 3; dickkopf homolog 3 (Xenopus laevis); Dickkopf-3; Dickkopf-related protein 3; DKK-3; DKK3; hDkk-3; regulated in glioma; REIC; RIG; RIG-like 5-6; RIG-like 7-1
Gene Aliases: DKK3; REIC; RIG; UNQ258/PRO295
UniProt ID: (Human) Q9UBP4
Entrez Gene ID: (Human) 27122
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