|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 219 of Human DLD|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27364 targets DLD in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27364 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 219 of Human DLD.
This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-oxo-glutarate complex; branched chain keto acid dehydrogenase complex; diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoyl dehydrogenase; Dihydrolipoyl dehydrogenase, mitochondrial; E3; E3 component of pyruvate dehydrogenase complex; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; GCSL; Glycine cleavage system L protein; glycine cleavage system protein L; LAD; lipoamide deh; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; mitochondrial; PHE3
Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3
UniProt ID: (Human) P09622
Entrez Gene ID: (Human) 1738
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