|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 202 and 419 of Human DPH2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30008 targets DPH2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30008 immunogen is recombinant fragment corresponding to a region within amino acids 202 and 419 of Human DPH2.
This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Diphthamide biosynthesis protein 2; diphthamide biosynthesis protein 2 homolog-like 2; diphthamide biosynthesis-like protein 2; Diphtheria toxin resistance protein 2; diptheria toxin resistance protein required for diphthamide biosynthesis-like 2; DPH2-like 2; DPH2L2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2
Gene Aliases: DPH2; DPH2L2
UniProt ID: (Human) Q9BQC3
Entrez Gene ID: (Human) 1802
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