|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||2-4 µg/ml|
|Tested Species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (16 GKEWTSTEKSREEDQQAS 33) of DPPA4 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Developmental pluripotency associated 4 (DPPA4) protein is abundantly found in embryonic stem cells and in early embryos. DPPA4 protein is localized in the embryonic stem cell nucleus associated with transcriptionally active chromatin. The Dppa4 gene overexpression does not support embryonic stem cell self-renewal but partially inhibits embryonic stem cell differentiation. Suppression of DPPA4 expression by short hairpin RNA induced embryonic stem cell into a primitive ectoderm lineage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2410091M23Rik; Developmental pluripotency-associated protein 4
Gene Aliases: 2410091M23Rik; DPPA4
UniProt ID: (Human) Q7L190
Entrez Gene ID: (Human) 55211
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