|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 9 and 238 of Human DREF|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27525 targets DREF in WB applications and shows reactivity with Human samples.
The PA5-27525 immunogen is recombinant fragment corresponding to a region within amino acids 9 and 238 of Human DREF.
This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5 and apos; untranslated region have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ac-like transposable element; ALTE; BED-type zinc finger domain-containing protein 1; DNA replication-related element binding factor; DREF; dREF homolog; hDREF; Putative Ac-like transposable element; Zinc finger BED domain-containing protein 1; zinc finger, BED-type containing 1
Gene Aliases: ALTE; DREF; hDREF; KIAA0785; TRAMP; ZBED1
UniProt ID: (Human) O96006
Entrez Gene ID: (Human) 9189
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