|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 211 and 448 of Human DUS2L|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31852 targets DUS2L in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31852 immunogen is recombinant fragment corresponding to a region within amino acids 211 and 448 of Human DUS2L.
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dihydrouridine synthase 2; dihydrouridine synthase 2-like, SMM1 homolog; DUS2; hDUS2; SMM1; SMM1 homolog; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; up-regulated in lung cancer 8; Up-regulated in lung cancer protein 8; URLC8
Gene Aliases: DUS2; DUS2L; SMM1; URLC8
UniProt ID: (Human) Q9NX74
Entrez Gene ID: (Human) 54920
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