|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 217 of Human DUSP19|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28007 targets DUSP19 in WB applications and shows reactivity with Human samples.
The PA5-28007 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 217 of Human DUSP19.
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dual specificity phosphatase TS-DSP1; Dual specificity protein phosphatase 19; DUSP17; LMW-DSP3; LMWDSP3; Low molecular weight dual specificity phosphatase 3; Protein phosphatase SKRP1; SAPK pathway-regulating phosphatase 1; SKRP1; stress-activated protein kinase pathway-regulating ph; Stress-activated protein kinase pathway-regulating phosphatase 1; TS-DSP1
Gene Aliases: DUSP17; DUSP19; LMWDSP3; SKRP1; TS-DSP1
UniProt ID: (Human) Q8WTR2
Entrez Gene ID: (Human) 142679
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.