|Immunohistochemistry (Paraffin) (IHC (P))||5-10 ug/ml|
|Western Blot (WB)||0.1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KIRNVIQGTELKS) corresponding to the C-terminus amino acids of DYX1C1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dynein, axonemal, assembly factor 4; dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; EKN1; FLJ37882; MGC70618; RD
Gene Aliases: CILD25; DNAAF4; DYX1; DYX1C1; DYXC1; EKN1; RD
UniProt ID: (Human) Q8WXU2
Entrez Gene ID: (Human) 161582
Molecular Function: chaperone
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