|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:100|
|Immunoprecipitation (IP)||5-10 ug|
|Western Blot (WB)||1-3 ug/ml|
|Immunocytochemistry (ICC)||See 2 publications below|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Western Blot (WB)||See 2 publications below|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human desmocollin-2 extracellular domain.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 130-kD pemphigus vulgaris antigen; ARVC10; ARVD10; Cadherin family member 2; Cadherin family member 3; cadherin family member 5; cadherin family member 6; CDHF5; CDHF6; CMD1BB; Desmocollin-2; Desmocollin-3; Desmocollin-4; desmoglein-2; desmoglein-3; Desmosomal glycoprotein II; desmosomal glycoprotein II/III; Desmosomal glycoprotein III; HT-CP; pemphigus vulgaris antigen
Gene Aliases: ARVD11; CDHF2; CDHF3; DG2; DGII/III; DSC; DSC1; DSC2; DSC3; DSC4; HT-CP
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