|Western Blot (WB)||1.0 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant SMAC, TIM22 proteins|
|Storage buffer||HEPES buffered saline|
|Contains||0.02% sodium azide|
|Storage conditions||4° C|
Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition. X linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/Diablo is expressed in a variety of tissues and has been identified as a negative regulator of XIAP. Smac/Diablo is a mitochondrial protein that enters the cytosol when cells undergo apoptosis, and moderates the caspase inhibition of IAPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 0610041G12Rik; DFNA64; diablo homolog; Diablo homolog, mitochondrial; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; Direct IAP-binding protein with low pI; mitochondrial; mitochondrial Smac protein; Second mitochondria-derived activator of caspase; SMAC; SMAC3
Gene Aliases: DFNA64; DIABLO; SMAC
UniProt ID: (Human) Q9HAV6
Entrez Gene ID: (Human) 56616
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