|Immunohistochemistry (Paraffin) (IHC (P))||8 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human DRD1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
This antibody is not recommended for use in ICC applications.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bovine, Pig, Opossum (100%).
The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D(1A) dopamine receptor; D-1 dopamine receptor; D1 dopamine receptor; D1a dopamine receptor; D1a receptor; DADR; Dopamine 1 receptor; Dopamine d-1 receptor; Dopamine D1 receptor; Dopamine d1a receptor; Dopamine receptor D1; Dopamine receptor d1a; Dopamine type 1 receptor; DRD1; DRD1A
Gene Aliases: DADR; DRD1; DRD1A
UniProt ID: (Human) P21728
Entrez Gene ID: (Human) 1812
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