|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 515-545 amino acids from the C-terminal region of human Dsk2|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chap1; DSK2 homolog; hPLIC-2; HRIHFB2157; Nedd4 binding protein 4; PLIC-2; Protein linking IAP with cytoskeleton 2; Protein linking IAP with cytoskeleton-2; Ubiquilin 2; Ubiquilin-2; Ubiquitin-like product Chap1/Dsk2
Gene Aliases: ALS15; CHAP1; DSK2; HRIHFB2157; N4BP4; PLIC2; UBQLN2
UniProt ID: (Human) Q9UHD9
Entrez Gene ID: (Human) 29978
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