|Immunohistochemistry (IHC)||Assay dependent|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||0.5 mg/ml|
|Tested Species reactivity||Bovine, Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant fragment, (His)6 tagged, corresponding to amino acids 1-750 of Human Dynamin 1.|
|Storage buffer||PBS with 40% glycerol, 0.1mM PMSF|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-91537 detects Dynamin 1 from mouse, human, bovine and rat samples.
MA1-91537 has been successfully used in immunohistochemistry, immunoprecipitation, Western blot applications.
The MA1-91537 immunogen is: Recombinant fragment, (His)6 tagged, corresponding to amino acids 1-750 of Human Dynamin 1.
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-dynamin; D100; DNM; Dynamin, brain; Dynamin-1
Gene Aliases: AI838169; BOS_12077; DNM; DNM1; EIEE31; Ftfl; Kiaa4093; mKIAA4093
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