|Immunohistochemistry (Paraffin) (IHC (P))||1:20|
|Western Blot (WB)||1:250|
|Immunohistochemistry (IHC)||See 6 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||E-cadherin and GST recombinant protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12547 targets E-Cadherin in IHC (P) applications and shows reactivity with Human samples.
The MA5-12547 immunogen is e-cadherin and GST recombinant protein.
E-cadherin (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); Cadherin-1; cadherin-E; calcium-dependent adhesion protein; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDHE; cell-CAM 120/80; E-Cadherin; E-cadherin 1; E-cadherin epithelial; ECAD; epithelial; Epithelial cadherin; LCAM; UVO; Uvomorulin
Gene Aliases: AA960649; Arc-1; CD324; CDH1; CDHE; E-cad; ECAD; L-CAM; LCAM; Um; UVO
Molecular Function: cadherin
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