|Gel Shift (GS)||1mg/mL|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20|
|Western Blot (WB)||1-2 µg/ml|
|Immunohistochemistry (IHC)||See 2 publications below|
|Western Blot (WB)||See 3 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human E2F-4 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11276 targets E2F-4 Transcription Factor in GS, IF, IHC (P), and WB applications and shows reactivity with Human and Rat samples.
The MA5-11276 immunogen is recombinant human E2F-4 protein.
E2F transcription factors are functionally regulated by binding to Rb p110, p107, and p130. E2F-4 is regulated by complex formation with Rb p110. E2F family members bind DNA as heterodimers with members of the DP family of polypeptides Differential phosphorylation contributes to the microheterogeniety of E2F-4 (total aa 411-416, varies due to a trinucleotide repeat).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E2F transcription factor 4, p107/p130-binding; E2F-4; p107/p130-binding protein; Transcription factor E2F4
Gene Aliases: 2010111M04Rik; AI427446; E2F-4; E2F4
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