|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 134 and 346 of Human EBP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30114 targets EBP1 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-30114 immunogen is recombinant fragment corresponding to a region within amino acids 134 and 346 of Human EBP1.
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell cycle protein p38-2G4 homolog; EBP1; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; HG4-1; IRES-specific cellular trans-acting factor 45 kDa; ITAF45; Mpp1; p38-2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; Proliferation-associated protein 1; Proliferation-associated protein 2G4; Protein p38-2G4
Gene Aliases: 38kDa; AA672939; EBP1; HG4-1; p38-2G4; PA2G4; Plfap
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