|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||polycomb protein embryonic ectoderm development|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA5-16313 targets EED in WB applications and shows reactivity with Human samples.
The MA5-16313 immunogen is polycomb protein embryonic ectoderm development.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: HEED; lethal, Chr 7, Rinchik 5; Polycomb protein EED; WAIT-1; WAIT1; WD protein associating with integrin cytoplasmic tails 1
Gene Aliases: EED; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lusk; WAIT1
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