|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 241 of Human EF-1alpha1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27660 targets EF-1alpha1 in WB applications and shows reactivity with Human samples.
The PA5-27660 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 241 of Human EF-1alpha1.
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CCS-3; CCS3; cervical cancer suppressor 3; CTCL tumor antigen; EE1A1; EEF-1; EEF1A; eEF1A-1; EF-1-alpha-1; EF-Tu; EF1A; EF1a-like protein; elongation factor 1 alpha subunit; Elongation factor 1-alpha 1; Elongation factor Tu; Eukaryotic elongation factor 1 A-1; eukaryotic translation elongation factor 1 alpha 1-like 14; glucocorticoid receptor AF-1 specific elongation factor; GRAF-1EF; HNGC:16303; LENG7; leukocyte receptor cluster (LRC) member 7; Leukocyte receptor cluster member 7; prostate tumor-inducing protein 1; PTI1; translation elongation factor 1 alpha 1-like 14
Gene Aliases: CCS-3; CCS3; EE1A1; EEF-1; EEF1A; eEF1A-1; EEF1A1; EF-Tu; EF1A; GRAF-1EF; HNGC:16303; LENG7; PTI1
UniProt ID: (Human) P68104
Entrez Gene ID: (Human) 1915
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