|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to an internal region of human EGFL7 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
Heat-mediated antigen retrieval is recommended prior to staining, using an EDTA buffer for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta tissue.
Epidermal growth factor-like protein 7 (EGFL7), also known as VE-statin, MEGF7, Notch4-like protein or Zneu1, is a 29.6 kDa protein produced and secreted by endothelium. The protein is also expressed by some normal and malignant tissues. The main function of EGFL7 is to regulate angiogenesis and vasculogenesis. A high level of EFGL-7 can be found in tissues with active angiogenesis of a variety of disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EGF-like protein 7; EGF-like-domain, multiple 7; Epidermal growth factor-like protein 7; Multiple EGF-like domains protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1; NOTCH4-like protein; RP11-251M1.2; Vascular endothelial statin; VE-STATIN; ZNEU1
Gene Aliases: EGFL7; MEGF7; NEU1; UNQ187/PRO1449; VE-STATIN; ZNEU1
UniProt ID: (Human) Q9UHF1
Entrez Gene ID: (Human) 51162
Molecular Function: calcium-binding protein
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