|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 141 and 407 of Human EGLN2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-32081 targets EGLN2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-32081 immunogen is recombinant fragment corresponding to a region within amino acids 141 and 407 of Human EGLN2.
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this posttranslational modification. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Egl nine homolog 2; egl-9 family hypoxia-inducible factor 2; EIT6; Estrogen-induced tag 6; HIF-PH1; HIF-prolyl hydroxylase 1; HIFPH1; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 1; PHD1; Prolyl hydroxylase domain-containing protein 1
Gene Aliases: EGLN2; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1
UniProt ID: (Human) Q96KS0
Entrez Gene ID: (Human) 112398
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