|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 217 and 454 of Human EIF2B epsilon|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29048 targets EIF2B epsilon in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-29048 immunogen is recombinant protein fragment corresponding to a region within amino acids 217 and 454 of Human EIF2B epsilon.
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CACH; EIF-2B; eIF-2B GDP-GTP exchange factor subunit epsilon; EIF2Bepsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; LVWM; Translation initiation factor eIF-2B subunit epsilon
Gene Aliases: C81315; CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
Molecular Function: G-protein modulator RNA binding protein enzyme modulator guanyl-nucleotide exchange factor nucleic acid binding nucleotidyltransferase transferase translation factor translation initiation factor
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