|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 210-238 amino acids from the central region of human ERCC8|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CKN1; Cockayne syndrome 1 homolog; Cockayne syndrome WD repeat protein CSA; Cockayne syndrome WD repeat protein CSA homolog; Cockayne syndrome WD-repeat protein CSA; CSA; DNA excision repair protein ERCC-8; excision repair cross-complementation group 8; excision repair cross-complementing rodent repair deficiency complementation group 8; excision repair cross-complementing rodent repair deficiency, complementation group 8
Gene Aliases: 2410022P04Rik; 2810431L23Rik; 4631412O06Rik; B130065P18Rik; CKN1; CSA; ERCC8; UVSS2
Molecular Function: receptor
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