|ChIP assay (ChIP)||Assay-dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human ERR alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28749 targets ERR alpha in WB and IP applications and shows reactivity with Human samples.
The PA5-28749 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human ERR alpha.
The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ERR-alpha; ERR1; ERRa; ERRalpha; ESRL1; Estrogen receptor-like 1; estrogen-related nuclear receptor alpha; Estrogen-related receptor alpha; NR3B1; Nuclear receptor subfamily 3 group B member 1; Steroid hormone receptor ERR1
Gene Aliases: ERR1; ERRa; ERRalpha; ESRL1; ESRRA; NR3B1
UniProt ID: (Human) P11474
Entrez Gene ID: (Human) 2101
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