|Western Blot (WB)||1:500|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide: Q(399) D K I F Q G N K D Y H K D V R N N(416)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-4270 detects ESDN from human, mouse and rat samples.
PA1-4270 has been successfully used in Western blot procedures.
PA1-4270 immunizing peptide corresponds to amino acid residues 399-416 from mouse and rat ESDN protein.
A novel protein ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. ESDN is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1700055P21Rik; coagulation factor V/VIII-homology domains protein 1; CUB; CUB and LCCL domain-containing protein 2; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; Discoidin; Discoidin, CUB and LCCL domain-containing protein 2; Endothelial and smooth muscle cell-derived neuropilin-like protein; LCCL and coagulation fac
Gene Aliases: 1700055P21Rik; AW146002; CLCP1; DCBLD2; ESDN
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter
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