|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488|
|Purification||Antigen affinity chromatography|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-27592 detects EWSR1 from human, mouse, and rat samples.
PA1-27592 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
Synthetic peptide corresponding to human RNA-binding protein EWSR1, amino acids 380-488
Might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking. or interfering with the normal function of CTD-POLII within the transcription initiation complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AC002059.7; bK984G1.4; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma homolog; Ewings sarcoma EWS-Fli1 (type 1) oncogene; EWS; EWS oncogene; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; RNA-binding protein EWS
Gene Aliases: bK984G1.4; EWS; EWS-FLI1; Ewsh; EWSR1
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