|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CBP-interacting protein 3; EXOSC8; Exosome complex component RRP43; Exosome complex exonuclease RRP43; Exosome component 8; OIP-2; OIP2; Opa interacting protein 2; Opa-interacting protein 2; p9; Ribosomal RNA-processing protein 43; RRP43
Gene Aliases: bA421P11.3; CIP3; EAP2; EXOSC8; OIP2; p9; PCH1C; RRP43; Rrp43p
UniProt ID: (Human) Q96B26
Entrez Gene ID: (Human) 11340
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